Cellular Metabolism Case Study

Cellular Metabolism Case Study Part 1: 1. Given the autopsy report the massive cell fill out in the kidneys, lungs, thymus, and heart indicate that the damage occurred at the cellular level, the parts of cellular respiration that occur in the mitochondrion. much than specifically, the poison directly affected the mitochondrion and in doing so it suggests that cellular respiration was disrupted. 2. The cellular deal that would be damage by arsenate would affect the cellular subroutine of glycolysis which occurs in the cytosol of a cell. In the information provided in the case study it states that arsenate manger replace inorganic phosphate in the timber of glycolysis that produces 1, 3-biphospholglycerate from glyceraldehyde 3-phosphate. This yields 1-arseno-3-phosphoglycerate. Therefore, glycolysis proceeds but the ATP molecule that would be generated from 1, 3-biophosphoglycerate is lost. 3. The cellular processes that would be impaired by rotenone would affect the cellular process of the negatron go chain which occurs within the mitochondrion of a cell. In information provided it states that rotenone is an agent that would inhibit the electron fuck chain within the mitochondrial therefore would affect the electron go chain. Part 2: 1.

I think that the specific cellular process that was affected by the poison was the first measuring rod in the electron transport chain. The very low levels of nicotinamide axerophthol dinucleotide+ and the high levels of NADH indicate that the initial step in the electron transport chain was disrupted. Particularly , the function of NADH dehydrogenase was inh! ibited by the rotenone poison. NADH dehydrogenase is manipulable for converting the electron carrier, NADH, to NAD+. 2. If NAD+ had been administered to the women, she probably could have non been saved. The low levels of NAD+ in the cells are simply a symptom of the poison. The problem is that the rotenone prevents the transfer of electrons from NADH to the electron transport...If you want to go deep a full essay, order it on our website: OrderCustomPaper.com

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